Skincare & cosmetics personalized epigenetic kits

The SKINTELLI test measures DNA methylation, a well-characterized epigenetic mechanism, of genes strongly correlated to skin quality factors and ultimately cosmetic properties. The degree of active or inactive states of your genes is dynamic and can be impacted by your skin’s exposure to the environment including the sun and, especially, the ingredients contained in skincare products. Epigenetic changes are naturally occurring as you age, but are also potentially reversible through proper environment stimuli. 

• We use our proprietary STEM-seq method (skin-targeted epigenetic marker sequencing), which combines next-generation DNA sequencing and bisulfite-based DNA methylation detection, to bring you results that you can count on. Other DNA tests use genotyping, which only looks at static genetic variants that don’t change since birth. Because skin is dynamic, we test for the epigenetic states of 40 genes that represent your current, not predisposed, skin quality.
• If you would like to see progress of your skin quality or regimen, SKINTELLI is a repeatable test. Your lifestyle and products used may affect the speed of which epigenetic changes occur such that they can be sufficiently detected by SKINTELLI. To account for this as well as any statistical deviations, we generally recommend one test every 6 months, although this may differ between users.
• You will gain three types of insights:

1. A profile snapshot that quantifies eight major skin quality factors in a 1-100 normalized score format. This score represents how active your genes are, with 100 being fully activated and 1 equivalent to complete inactivation. This calculation is based on an epigenetic mechanism known as DNA methylation, which controls gene activity.
2. An in-depth explanation of what each of the eight skin quality factor means, and which skincare product ingredients can help to improve each factor. This general guidance offers you flexibility in making your own shopping decisions for brands.
3. Products that are algorithmically matched to your skin profile based on the most optimal ingredient compositions that can optimally address all quality factors as a whole. You will receive 36 matches, ranging from brand name to indie boutique, which are separated into three price tiers.

SKINTELLI is currently available in the USA in all states except New York and Maryland. The test may be made available to NY and MD residents as well as worldwide in the near future.