Biological age is a measure of lifestyle, habits, and innate factors that cause us to age. How an individual’s biological age should be measured and what factors should be included and weighted to calculate a biological age continues to be of great interest to researchers. Today, it is understood that individuals experience different rates of aging resulting from progressive deterioration, occurring simultaneously at the molecular, cellular, tissue, organ, and functional levels. This is...
Tobacco use remains one of the most important risk factors for developing serious conditions such as heart disease, lung disease, and cancer. Due to its influence on health, underwriting places significant value on identifying tobacco exposure among life insurance applicants. Accordingly, the life insurance industry widely screens for tobacco use by testing with the biomarker cotinine, a metabolite of nicotine, in an applicant’s clinical chemistry panel. The challenge with measuring cotinine...
Epigenetics is an area where our scientific knowledge is rapidly increasing. One thing that scientists have discovered is that epigenetic errors are common in diseases such as cancer and in ageing cells. As a result, scientists are developing medicines that target faulty epigenomes and one of the first examples is the use of HDAC inhibitors, similar to the compound found in royal jelly. From the study of strange patterns of inheritance such as genetic imprinting, the yellow/agouti Avy mouse,...